30 Day

The Rise & Repeat Study: Daily Tadalafil for Nighttime Erections

STUDY TITLE The Rise & Repeat Study: Daily Tadalafil for Nighttime Erections
Submitted under umbrella

Minimal Risk Citizen Science Umbrella Protocol

Date submitted

-

End date

There is no pre-specified end date and sub-studies remain open long-term.

Language

English

Efforia AI IRB approval recommendation

Recruitment page preview

Preview

Author edit

Edit

Informed consent

Review

Study author

Christos Konstantinidis, Jordan Tsanev, Matthew Amsden

Principal investigator

Matthew Amsden

Sub-Investigator for Adverse Events

Dr. Viral Patel

Description

Yes, a study on your nighttime wood. Nocturnal erections—aka nighttime tumescence—are a key signal of cardiovascular & hormonal health. This study looks at whether taking 2.5mg of tadalafil daily for 30 days can boost this vital function. You'll track results with the Adam Sensor, the world’s first erection health monitor & some questionnaire. The goal? To see if low-dose tadalafil keep your engine running and mind humming even while you sleep.

Participant engagement length

30 Days

Sponsor

This study is made possible by your payment to cover all supplies and expenses required to participate.

Cost to participant

$0

Included products & services
Adam Sensor – Nocturnal Erection Tracker: $149
Outcome measures

Adam Sensor: Nocturnal Penile Tumescence

International Index of Erectile Function Survey

Body Image and Self-Perception Survey

Methodology

Single Arm longitudinal where participants act as their own control

Basic or advanced dissemination plan

Basic

Deviation from recruitment approach

No

Deviation from statistical approach

No

Will study include “more about you questions”

No

Clinicaltrials.Gov

Yes

Committment to list findings on clinicaltrials.Gov

Yes

This document is prepared with the assistance of AI, but is reviewed by a human.

Rational & Study Design

Why I Created This Study:

Let’s talk about something men don’t often talk about—nighttime erections. They’re not just a biological oddity; they’re a vital sign of cardiovascular and hormonal health. But despite what social media influencers and clickbait headlines might say, we still don’t have solid, real-world data on whether daily low-dose tadalafil (2.5mg) actually makes a difference.

As the founder of Adam Health—the team behind the world’s first erection health tracker—I built this study to change that. We're not guessing. We’re measuring. With the Adam Sensor, we’re tracking what happens when men take control of their nighttime wood—and their long-term sexual confidence. No fluff. Just real data from real men.

What’s In It For You: This is about you understanding your own body—not some average from a lab study buried in footnotes. You’ll get hard data (pun intended) on how your body responds to daily low-dose tadalafil. You’ll see changes in your nocturnal erections, but also in how you feel about yourself. Confidence. Vitality. Drive.

What We’re Testing: We’re studying how a 2.5mg daily dose of tadalafil affects. First, The frequency and quality of your nocturnal erections, and second, your self-perception and body confidence (measured with validated tools like the IIEF and BISQ). The Adam Sensor gives us the objective data. Your feedback gives us the full picture.

Why It Matters:

Most men only think about erections when they don’t happen. But what if your best sexual health hack is happening while you sleep? This study has the potential to reshape how we think about performance, confidence, and preventative care. It's short—just 30 days—but it could give you lifelong insights. Yes, individual responses will vary. But the chance to turn curiosity into clarity? That’s a win.

The Intervention

Tadalafil, a phosphodiesterase type 5 inhibitor, is widely recognized in the medical community for treating erectile dysfunction, with evidence supporting its ability to enhance blood flow and improve erectile function. The scientific consensus acknowledges its safety and efficacy when used appropriately. Social media often highlights its benefits for sexual health, contributing to public interest. General belief supports its use for boosting confidence and vitality, though awareness of potential side effects, like headaches or flushing, is advised.

Included Products & Services

Product Name: Adam Sensor – Nocturnal Erection Tracker

Quantity included: 1

Price: $149.00

Product Description: You monitor your steps, calories, and even your credit score. Now, it's time to keep an eye on something crucial for many—your manhood's health. The Adam Sensor offers advanced technology to track erection health and gives you a chance to join leading studies in male wellness, uncovering new insights.

Product Image:

Ingredients:

Product Safety:

Study Design & Methodology

Inappropriate Participants & Inclusion/Exclusion

Study Design & Experience

Statistical Analysis Plan

Limitations & Justification

Human Subjects Ethics

Suitability Under Minimal Risk Umbrella Protocol

Suitability for Pay to Participate Model

Human Subjects Protection Questionnaire