60 Day

Energy Enhancement for Marathon Runners with NAD+ Supplements

STUDY TITLE Energy Enhancement for Marathon Runners with NAD+ Supplements
Submitted under umbrella

Umbrella Protocol for Efforia Personalized Agentic Hypothesis Discovery & Experiential Proof Trials

Date submitted

—

End date

There is no pre-specified end date and sub-studies remain open long-term.

Language

English

Efforia AI IRB approval recommendation

—

Recruitment page preview

Preview

Informed consent

Review

Study author

Matthew Amsden

Principal investigator

Matthew Amsden

Sub-Investigator for Adverse Events

Dr. Viral Patel

Description

This protocol involves a daily supplementation routine using NAD+ to enhance energy levels and support the training schedule for marathon runners. The focus is on optimizing energy and endurance through consistent supplementation. Participants will follow a structured training regimen to complement the supplementation.

Participant engagement length

60 Days

Sponsor

This study is made possible by your payment to cover all supplies and expenses required to participate.

Cost to participant

$0

Included products & services
NAD+ 100–300 mg per day (oral; liposomal or sublingual preferred): $0
Outcome measures

PROMIS Sleep Disturbance Scale

PROMIS Short Form v1.0 – Fatigue 8a

Methodology

Single Arm longitudinal where participants act as their own control

Basic or advanced dissemination plan

Basic

Deviation from recruitment approach

No

Deviation from statistical approach

No

Will study include “more about you questions”

No

ClinicalTrials.gov

Yes

Commitment to list findings on ClinicalTrials.gov

Yes

This document is prepared with the assistance of AI, but is reviewed by a human.

Rational & Study Design

Why I Created This Study:

In the ever-evolving world of marathon running, energy is the currency of champions. While many runners chase the next best supplement, NAD+ has been creating a buzz. Emerging research suggests NAD+ may boost cellular energy production, and runners on forums swear by its endurance-enhancing effects. But does it truly make a difference? This study seeks to untangle the truth, marrying science with folklore, to optimize the marathon experience and propel runners to new personal bests.

My Objective for You:

As a marathon runner, your goal is not just to finish but to finish strong. Our objective for you is to enhance your energy levels and improve your running performance through NAD+ supplementation. With this protocol, you'll gain insights into how NAD+ impacts your endurance, helping you maximize your training and achieve undeniable results on your journey to the finish line.

Aims & Objectives:

Our aim is to evaluate the impact of NAD+ supplementation on energy and endurance in marathon runners. By participating, you'll receive personalized insights on how this regimen can transform your training and performance, empowering you with data-driven decisions about your supplementation choices for future races.

Significance & Impact:

This study's significance lies in its potential to redefine energy optimization for marathon runners. By exploring NAD+ supplementation, we expect to provide evidence-based insights into its effectiveness on sleep, fatigue, and endurance. While limitations include individual variability, the findings will pave the way for personalized supplementation strategies, enhancing both training and performance outcomes in the running community.

The Intervention

Included Products & Services

Product Name: NAD+ 100–300 mg per day (oral; liposomal or sublingual preferred)

Quantity included: 0

Price: $0.00

Product Description: A molecule critical for cellular energy production, DNA repair, and healthy aging.

Product Image: NAD+ 100–300 mg per day (oral; liposomal or sublingual preferred)

Ingredients:

Product Safety:

Study Design & Methodology

Inappropriate Participants & Inclusion/Exclusion

Study Design & Experience

Statistical Analysis Plan

Limitations & Justification

Human Subjects Ethics

Suitability Under Minimal Risk Umbrella Protocol

Suitability for Pay to Participate Model

Human Subjects Protection Questionnaire